Molecular Formula | C21H22F2N4O4 |
Molar Mass | 432.42 |
Density | 1.441±0.06 g/cm3(Predicted) |
pKa | 6.88±0.60(Predicted) |
Storage Condition | 2-8℃ |
Use | HIV-1 integrase inhibitor 3 is a HIV-1 integrase chain transfer (INST) inhibitor with an IC50 value of 2.7 nM. |
In vitro study | HIV-1 integrase inhibitor 3 (compound 4c) is a HIV-1 integrase strand transfer (INST) inhibitor with an IC 50 of 2.7 nM. HIV-1 integrase inhibitor 3 also displays an antiviral inhibitory potency against the Q148H/G140S mutant with an EC 50 of 7 nM. |